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Fast and Accurate Shared Segment Detection and Relatedness Estimation in Un-phased Genetic Data via TRUFFLE
Relationship estimation and segment detection between individuals is an important aspect of disease gene mapping. Existing methods are either tailored for computational efficiency or require phasing to improve accuracy. We developed TRUFFLE, a method that integrates computational techniques and stat...
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| Publicado no: | Am J Hum Genet |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6612710/ https://ncbi.nlm.nih.gov/pubmed/31178127 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2019.05.007 |
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