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Empirical Bayes Correction for the Winner's Curse in Genetic Association Studies
We consider an Empirical Bayes method to correct for the Winner's Curse phenomenon in genome-wide association studies. Our method utilizes the collective distribution of all odds ratios (ORs) to determine the appropriate correction for a particular single-nucleotide polymorphism (SNP). We can s...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4048064/ https://ncbi.nlm.nih.gov/pubmed/23012258 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.21683 |
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