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Resampling to Address the Winner's Curse in Genetic Association Analysis of Time to Event

The “winner's curse” is a subtle and difficult problem in interpretation of genetic association, in which association estimates from large‐scale gene detection studies are larger in magnitude than those from subsequent replication studies. This is practically important because use of a biased e...

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Detalhes bibliográficos
Publicado no:Genet Epidemiol
Main Authors: Poirier, Julia G., Faye, Laura L., Dimitromanolakis, Apostolos, Paterson, Andrew D., Sun, Lei, Bull, Shelley B.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4609263/
https://ncbi.nlm.nih.gov/pubmed/26411674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.21920
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