A gene regulatory network cooperatively controlled by Pdx1 and Sox9 governs lineage allocation of foregut progenitor cells

The generation of pancreas, liver and intestine from a common pool of progenitors in the foregut endoderm requires the establishment of organ boundaries. How dorsal foregut progenitors activate pancreatic genes and evade the intestinal lineage choice remains unclear. We here identify Pdx1 and Sox9 a...

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Gepubliceerd in:Cell Rep
Hoofdauteurs: Shih, Hung Ping, Seymour, Philip A., Patel, Nisha A., Xie, Ruiyu, Wang, Allen, Liu, Patrick P., Yeo, Gene W., Magnuson, Mark A., Sander, Maike
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2015
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4607666/
https://ncbi.nlm.nih.gov/pubmed/26440894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.08.082
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