Sox2 Cooperates with Inflammation-Mediated Stat3 Activation in the Malignant Transformation of Foregut Basal Progenitor Cells

Sox2 regulates the self-renewal of multiple types of stem cells. Recent studies suggest it also plays oncogenic roles in the formation of squamous carcinoma in several organs, including the esophagus where Sox2 is predominantly expressed in the basal progenitor cells of the stratified epithelium. He...

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Autors principals: Liu, Kuancan, Jiang, Ming, Lu, Yun, Chen, Hao, Sun, Jun, Wu, Shaoping, Ku, Wei-Yao, Nakagawa, Hiroshi, Kita, Yoshiaki, Natsugoe, Shoji, Peters, Jeffrey H., Rustgi, Anil, Onaitis, Mark W., Kiernan, Amy, Chen, Xiaoxin, Que, Jianwen
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3594795/
https://ncbi.nlm.nih.gov/pubmed/23472872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2013.01.007
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