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Multiple dose-dependent roles for Sox2 in the patterning and differentiation of anterior foregut endoderm
Sox2 is expressed in developing foregut endoderm, with highest levels in the future esophagus and anterior stomach. By contrast, Nkx2.1 (Titf1) is expressed ventrally, in the future trachea. In humans, heterozygosity for SOX2 is associated with anopthalmiaesophageal-genital syndrome (OMIM 600992), a...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3625644/ https://ncbi.nlm.nih.gov/pubmed/17522155 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.003855 |
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