BMP-driven NRF2 activation in esophageal basal cell differentiation and eosinophilic esophagitis

Tissue homeostasis requires balanced self-renewal and differentiation of stem/progenitor cells, especially in tissues that are constantly replenished like the esophagus. Disruption of this balance is associated with pathological conditions, including eosinophilic esophagitis (EoE), in which basal pr...

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Dettagli Bibliografici
Pubblicato in:J Clin Invest
Autori principali: Jiang, Ming, Ku, Wei-Yao, Zhou, Zhongren, Dellon, Evan S., Falk, Gary W., Nakagawa, Hiroshi, Wang, Mei-Lun, Liu, Kuancan, Wang, Jun, Katzka, David A., Peters, Jeffrey H., Lan, Xiaopeng, Que, Jianwen
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2015
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4396468/
https://ncbi.nlm.nih.gov/pubmed/25774506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI78850
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