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A Sox9/Fgf feed-forward loop maintains pancreatic organ identity

All mature pancreatic cell types arise from organ-specific multipotent progenitor cells. Although previous studies have identified cell-intrinsic and -extrinsic cues for progenitor cell expansion, it is unclear how these cues are integrated within the niche of the developing organ. Here, we present...

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Detalhes bibliográficos
Main Authors: Seymour, Philip A., Shih, Hung Ping, Patel, Nisha A., Freude, Kristine K., Xie, Ruiyu, Lim, Christopher J., Sander, Maike
Formato: Artigo
Idioma:Inglês
Publicado em: Company of Biologists 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3424044/
https://ncbi.nlm.nih.gov/pubmed/22874919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.078733
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