A gene regulatory network cooperatively controlled by Pdx1 and Sox9 governs lineage allocation of foregut progenitor cells

The generation of pancreas, liver and intestine from a common pool of progenitors in the foregut endoderm requires the establishment of organ boundaries. How dorsal foregut progenitors activate pancreatic genes and evade the intestinal lineage choice remains unclear. We here identify Pdx1 and Sox9 a...

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Pubblicato in:Cell Rep
Autori principali: Shih, Hung Ping, Seymour, Philip A., Patel, Nisha A., Xie, Ruiyu, Wang, Allen, Liu, Patrick P., Yeo, Gene W., Magnuson, Mark A., Sander, Maike
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4607666/
https://ncbi.nlm.nih.gov/pubmed/26440894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.08.082
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