SOX9 is required for maintenance of the pancreatic progenitor cell pool

The factors necessary to maintain organ-specific progenitor cells are poorly understood and yet of extreme clinical importance. Here, we identify the transcription factor SOX9 as the first specific marker and maintenance factor of multipotential progenitors during pancreas organogenesis. In the deve...

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Bibliografiske detaljer
Main Authors: Seymour, Philip A., Freude, Kristine K., Tran, Man N., Mayes, Erin E., Jensen, Jan, Kist, Ralf, Scherer, Gerd, Sander, Maike
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2007
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1794281/
https://ncbi.nlm.nih.gov/pubmed/17267606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0609217104
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