A gene regulatory network cooperatively controlled by Pdx1 and Sox9 governs lineage allocation of foregut progenitor cells

The generation of pancreas, liver and intestine from a common pool of progenitors in the foregut endoderm requires the establishment of organ boundaries. How dorsal foregut progenitors activate pancreatic genes and evade the intestinal lineage choice remains unclear. We here identify Pdx1 and Sox9 a...

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Publicado en:Cell Rep
Main Authors: Shih, Hung Ping, Seymour, Philip A., Patel, Nisha A., Xie, Ruiyu, Wang, Allen, Liu, Patrick P., Yeo, Gene W., Magnuson, Mark A., Sander, Maike
Formato: Artigo
Idioma:Inglês
Publicado: 2015
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4607666/
https://ncbi.nlm.nih.gov/pubmed/26440894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.08.082
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