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Design, Synthesis and Pharmacological Characterization of a Fluorescent Agonist of the P2Y(14) Receptor
The P2Y(14)R is a G(i/o)-coupled receptor of the P2Y family of purinergic receptors that is activated by extracellular UDP and UDP-glucose (UDPG). In an earlier report we described a P2Y(14)R fluorescent probe, MRS4174, based on the potent and selective antagonist PPTN, a naphthoic acid derivative....
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| Vydáno v: | Bioorg Med Chem Lett |
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| Hlavní autoři: | , , , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2015
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4607650/ https://ncbi.nlm.nih.gov/pubmed/26303895 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2015.08.021 |
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