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Migration of PIP(2) lipids on voltage-gated potassium channel surface influences channel deactivation
Published studies of lipid-protein interactions have mainly focused on lipid binding to an individual site of the protein. Here, we show that a lipid can migrate between different binding sites in a protein and this migration modulates protein function. Voltage-gated potassium (Kv) channels have sev...
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| Pubblicato in: | Sci Rep |
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| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4606798/ https://ncbi.nlm.nih.gov/pubmed/26469389 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep15079 |
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