The gating charge pathway of an epilepsy-associated potassium channel accommodates chemical ligands

Voltage-gated potassium (Kv) channels derive their voltage sensitivity from movement of gating charges in voltage-sensor domains (VSDs). The gating charges translocate through a physical pathway in the VSD to open or close the channel. Previous studies showed that the gating charge pathways of Shake...

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Detalhes bibliográficos
Main Authors: Li, Ping, Chen, Zhuxi, Xu, Haiyan, Sun, Haifeng, Li, Hao, Liu, Hong, Yang, Huaiyu, Gao, Zhaobing, Jiang, Hualiang, Li, Min
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3773576/
https://ncbi.nlm.nih.gov/pubmed/23797855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2013.82
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