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Migration of PIP(2) lipids on voltage-gated potassium channel surface influences channel deactivation
Published studies of lipid-protein interactions have mainly focused on lipid binding to an individual site of the protein. Here, we show that a lipid can migrate between different binding sites in a protein and this migration modulates protein function. Voltage-gated potassium (Kv) channels have sev...
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| Publicat a: | Sci Rep |
|---|---|
| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4606798/ https://ncbi.nlm.nih.gov/pubmed/26469389 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep15079 |
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