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Lipid-dependent gating of a voltage-gated potassium channel

Recent studies hypothesized that phospholipids stabilize two voltage-sensing arginine residues of certain voltage-gated potassium channels in activated conformations. It remains unclear how lipids directly affect these channels. Here, by examining the conformations of the KvAP in different lipids, w...

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Autori principali: Zheng, Hui, Liu, Weiran, Anderson, Lingyan Y., Jiang, Qiu-Xing
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3072105/
https://ncbi.nlm.nih.gov/pubmed/21427721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms1254
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