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Combinatorial augmentation of voltage-gated KCNQ potassium channels by chemical openers

Noninactivating potassium current formed by KCNQ2 (Kv7.2) and KCNQ3 (Kv7.3) subunits resembles neuronal M-currents which are activated by voltage and play a critical role in controlling membrane excitability. Activation of voltage-gated potassium channels by a chemical opener is uncommon. Therefore,...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Xiong, Qiaojie, Sun, Haiyan, Zhang, Yangming, Nan, Fajun, Li, Min
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2268596/
https://ncbi.nlm.nih.gov/pubmed/18272489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0712256105
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