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26-Desmethyl-2-methylene-22-ene-19-nor-1α,25-dihydroxyvitamin D(3) compounds selectively active on intestine

Six new analogs of 2-methylene-19-nor-1α,25-dihydroxyvitamin D(3), 6–7 and 8a,b–9a,b, have been synthesized. All compounds are characterized by a trans double bond located in the side chain between C-22 and C-23. While compounds 6 and 7 possess C-26 and C-27 methyls, compounds 8a,b and 9a,b lack one...

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Dettagli Bibliografici
Pubblicato in:Steroids
Autori principali: Chiellini, Grazia, Grzywacz, Pawel, Plum, Lori A., Clagett-Dame, Margaret, DeLuca, Hector F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4601567/
https://ncbi.nlm.nih.gov/pubmed/24513051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.steroids.2014.01.012
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