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Synthesis and biological properties of 2-methylene-19-nor-25-dehydro-1α-hydroxyvitamin D(3)-26,23-lactones—weak agonists
In a continuing effort to explore the 2-methylene-1α-hydroxy-19-norvitamin D3 class of pharmacologically important vitamin D compounds, two novel 2-methylene-19-nor-25-dehydro-1α-hydroxyvitamin D(3)-26,23-lactones, GC-3 and HLV, were synthesized and biologically tested. Based on reports of similarly...
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| Publié dans: | Bioorg Med Chem |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2008
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4601569/ https://ncbi.nlm.nih.gov/pubmed/18722130 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2008.08.011 |
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