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Drugging the Ral GTPase

The RAL GTPases have emerged as important drivers of tumor growth and metastasis in lung, colon, pancreatic and other cancers. We recently developed the first small molecule inhibitors of RAL that exhibited antitumor activity in human lung cancer cell lines. These compounds are non-competitive inhib...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Small GTPases
Prif Awduron: Yan, Chao, Jones, David NM, Theodorescu, Dan
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Taylor & Francis 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4601353/
https://ncbi.nlm.nih.gov/pubmed/26280620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21541248.2015.1018403
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