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Transcriptional signatures of Ral GTPase are associated with aggressive clinicopathologic characteristics in human cancer

RalA and RalB are small GTPases which support malignant development and progression in experimental models of bladder, prostate and squamous cancer. However, demonstration of their clinical relevance in human tumors remains lacking. Here, we developed tools to evaluate Ral protein expression, activa...

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Bibliographic Details
Main Authors: Smith, Steven C., Baras, Alexander S., Owens, Charles R., Dancik, Garrett, Theodorescu, Dan
Format: Artigo
Language:Inglês
Published: 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3842017/
https://ncbi.nlm.nih.gov/pubmed/22586063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-11-3966
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