Drugging the Ral GTPase

The RAL GTPases have emerged as important drivers of tumor growth and metastasis in lung, colon, pancreatic and other cancers. We recently developed the first small molecule inhibitors of RAL that exhibited antitumor activity in human lung cancer cell lines. These compounds are non-competitive inhib...

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Bibliografiske detaljer
Udgivet i:Small GTPases
Main Authors: Yan, Chao, Jones, David NM, Theodorescu, Dan
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2015
Fag:
Commentary
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4601353/
https://ncbi.nlm.nih.gov/pubmed/26280620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21541248.2015.1018403
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