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Drugging the Ral GTPase
The RAL GTPases have emerged as important drivers of tumor growth and metastasis in lung, colon, pancreatic and other cancers. We recently developed the first small molecule inhibitors of RAL that exhibited antitumor activity in human lung cancer cell lines. These compounds are non-competitive inhib...
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| Publicado no: | Small GTPases |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4601353/ https://ncbi.nlm.nih.gov/pubmed/26280620 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21541248.2015.1018403 |
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