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RAL GTPases: Biology and Potential as Therapeutic Targets in Cancer

More than a hundred proteins comprise the RAS superfamily of small GTPases. This family can be divided into RAS, RHO, RAB, RAN, ARF, and RAD subfamilies, with each shown to play distinct roles in human cells in both health and disease. The RAS subfamily has a well-established role in human cancer wi...

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Detalhes bibliográficos
Publicado no:Pharmacol Rev
Main Authors: Yan, Chao, Theodorescu, Dan
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5712631/
https://ncbi.nlm.nih.gov/pubmed/29196555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/pr.117.014415
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