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RAL GTPases: Biology and Potential as Therapeutic Targets in Cancer
More than a hundred proteins comprise the RAS superfamily of small GTPases. This family can be divided into RAS, RHO, RAB, RAN, ARF, and RAD subfamilies, with each shown to play distinct roles in human cells in both health and disease. The RAS subfamily has a well-established role in human cancer wi...
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Publicado no: | Pharmacol Rev |
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Main Authors: | , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
The American Society for Pharmacology and Experimental Therapeutics
2018
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5712631/ https://ncbi.nlm.nih.gov/pubmed/29196555 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/pr.117.014415 |
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