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Synthesis of novel Ral inhibitors: an in vitro and in vivo study
Chemical synthesis was performed to produce a series of 6-amino-1,3-disubstituted-4-phenyl-1,4-dihydro pyrano[2,3-c]pyrazole-5-carbonitrile compounds (14 – 57) which were characterized by (1)H-NMR, (13)C-NMR and LC/MS-MS. These compounds were assessed for their effect on the in vitro anchorage indep...
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| Publié dans: | Bioorg Med Chem Lett |
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| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5301652/ https://ncbi.nlm.nih.gov/pubmed/27825764 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2016.10.021 |
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