Potent human uric acid transporter 1 inhibitors: in vitro and in vivo metabolism and pharmacokinetic studies

Human uric acid transporter 1 (hURAT1; SLC22A12) is a very important urate anion exchanger. Elevated urate levels are known to play a pivotal role in cardiovascular diseases, chronic renal disease, diabetes, and hypertension. Therefore, the development of potent uric acid transport inhibitors may le...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Wempe, Michael F, Lightner, Janet W, Miller, Bettina, Iwen, Timothy J, Rice, Peter J, Wakui, Shin, Anzai, Naohiko, Jutabha, Promsuk, Endou, Hitoshi
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2012
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3496402/
https://ncbi.nlm.nih.gov/pubmed/23152669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S35805
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados