A Novel Transporter of SLC22 Family Specifically Transports Prostaglandins and Co-localizes with 15-Hydroxyprostaglandin Dehydrogenase in Renal Proximal Tubules

We identified a novel prostaglandin (PG)-specific organic anion transporter (OAT) in the OAT group of the SLC22 family. The transporter designated OAT-PG from mouse kidney exhibited Na(+)-independent and saturable transport of PGE(2) when expressed in a proximal tubule cell line (S(2)). Unusual for...

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Detalhes bibliográficos
Main Authors: Shiraya, Katsuko, Hirata, Taku, Hatano, Ryo, Nagamori, Shushi, Wiriyasermkul, Pattama, Jutabha, Promsuk, Matsubara, Mitsunobu, Muto, Shigeaki, Tanaka, Hidekazu, Asano, Shinji, Anzai, Naohiko, Endou, Hitoshi, Yamada, Akira, Sakurai, Hiroyuki, Kanai, Yoshikatsu
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Membrane Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2903351/
https://ncbi.nlm.nih.gov/pubmed/20448048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.084426
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