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Establishment of Stable Cell Lines With High Expression of Heterodimers of Human 4F2hc and Human Amino Acid Transporter LAT1 or LAT2 and Delineation of Their Differential Interaction With α-Alkyl Moieties

System L is a major transport system for cellular uptake of neutral amino acids. Among system L transporters, L-type amino acid transporter 1 (LAT1) is responsible for the nutrient uptake in cancer cells, whereas L-type amino acid transporter 2 (LAT2) is a transporter for non-cancer cells. In this s...

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Detalhes bibliográficos
Publicado no:J Pharmacol Sci
Main Authors: Khunweeraphong, Narakorn, Nagamori, Shushi, Wiriyasermkul, Pattama, Nishinaka, Yumiko, Wongthai, Printip, Ohgaki, Ryuichi, Tanaka, Hidekazu, Tominaga, Hideyuki, Sakurai, Hiroyuki, Kanai, Yoshikatsu
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier B.V. Production and hosting by Elsevier B.V. 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7128428/
https://ncbi.nlm.nih.gov/pubmed/22850614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1254/jphs.12124FP
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