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A Cell Of Origin gene signature indicates human bladder cancer has distinct cellular progenitors

There are two distinct forms of urothelial (bladder) cancer: muscle-invasive (MI) and non-muscle invasive (NMI) disease. Since it is currently believed that bladder cancer arises by transformation of urothelial cells of the basal layer, bladder cancer stem cells (CSCs) have been isolated based on ex...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Dancik, Garrett M., Owens, Charles R., Iczkowski, Kenneth A., Theodorescu, Dan
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3960367/
https://ncbi.nlm.nih.gov/pubmed/24357085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.1625
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