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A Cell Of Origin gene signature indicates human bladder cancer has distinct cellular progenitors

There are two distinct forms of urothelial (bladder) cancer: muscle-invasive (MI) and non-muscle invasive (NMI) disease. Since it is currently believed that bladder cancer arises by transformation of urothelial cells of the basal layer, bladder cancer stem cells (CSCs) have been isolated based on ex...

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Main Authors: Dancik, Garrett M., Owens, Charles R., Iczkowski, Kenneth A., Theodorescu, Dan
格式: Artigo
語言:Inglês
出版: 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3960367/
https://ncbi.nlm.nih.gov/pubmed/24357085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.1625
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