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A Cell Of Origin gene signature indicates human bladder cancer has distinct cellular progenitors

There are two distinct forms of urothelial (bladder) cancer: muscle-invasive (MI) and non-muscle invasive (NMI) disease. Since it is currently believed that bladder cancer arises by transformation of urothelial cells of the basal layer, bladder cancer stem cells (CSCs) have been isolated based on ex...

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Bibliographic Details
Main Authors: Dancik, Garrett M., Owens, Charles R., Iczkowski, Kenneth A., Theodorescu, Dan
Format: Artigo
Language:Inglês
Published: 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3960367/
https://ncbi.nlm.nih.gov/pubmed/24357085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.1625
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