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Functional Impact of Chromatin Remodeling Gene Mutations and Predictive Signature for Therapeutic Response in Bladder Cancer

Urothelial carcinoma accounts for most of the bladder cancer cases. Using next-generation sequencing (NGS) technology, we found that a significant percentage (83%) of tumors had mutations in chromatin-remodeling genes. Here, we examined the functional relevance of mutations in two chromatin-remodeli...

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Bibliografiske detaljer
Udgivet i:Mol Cancer Res
Main Authors: Duex, Jason E., Swain, Kalin E, Dancik, Garrett M., Paucek, Richard D., Owens, Charles, Churchill, Mair E.A., Theodorescu, Dan
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5951683/
https://ncbi.nlm.nih.gov/pubmed/28970362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-17-0260
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