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Strategies for imputing and analyzing rare variants in association studies

Rare genetic variants may be responsible for a significant amount of the uncharacterized genetic risk underlying many diseases. An efficient approach to characterizing the disease burden of rare variants may be to impute them into existing large datasets. It is well-known that the ability to impute...

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Detaylı Bibliyografya
Yayımlandı:Trends Genet
Asıl Yazarlar: Hoffmann, Thomas J., Witte, John S.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4600126/
https://ncbi.nlm.nih.gov/pubmed/26450338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tig.2015.07.006
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