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Comprehensive Approach to Analyzing Rare Genetic Variants

Recent findings suggest that rare variants play an important role in both monogenic and common diseases. Due to their rarity, however, it remains unclear how to appropriately analyze the association between such variants and disease. A common approach entails combining rare variants together based o...

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Detalhes bibliográficos
Main Authors: Hoffmann, Thomas J., Marini, Nicholas J., Witte, John S.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2972202/
https://ncbi.nlm.nih.gov/pubmed/21072163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0013584
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