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Statistical Analysis Strategies for Association Studies Involving Rare Variants

The limitations of genome-wide association (GWA) studies that focus on the phenotypic influence of common genetic variants have motivated human geneticists to consider the contribution of rare variants to phenotypic expression. The increasing availability of high-throughput sequencing technology has...

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Detalhes bibliográficos
Main Authors: Bansal, Vikas, Libiger, Ondrej, Torkamani, Ali, Schork, Nicholas J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3743540/
https://ncbi.nlm.nih.gov/pubmed/20940738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrg2867
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