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Rare-Variant Association Analysis: Study Designs and Statistical Tests

Despite the extensive discovery of trait- and disease-associated common variants, much of the genetic contribution to complex traits remains unexplained. Rare variants can explain additional disease risk or trait variability. An increasing number of studies are underway to identify trait- and diseas...

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Hlavní autoři: Lee, Seunggeung, Abecasis, Gonçalo R., Boehnke, Michael, Lin, Xihong
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4085641/
https://ncbi.nlm.nih.gov/pubmed/24995866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2014.06.009
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