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General Framework for Meta-analysis of Rare Variants in Sequencing Association Studies

We propose a general statistical framework for meta-analysis of gene- or region-based multimarker rare variant association tests in sequencing association studies. In genome-wide association studies, single-marker meta-analysis has been widely used to increase statistical power by combining results...

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Bibliografski detalji
Glavni autori: Lee, Seunggeun, Teslovich, Tanya M., Boehnke, Michael, Lin, Xihong
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3710762/
https://ncbi.nlm.nih.gov/pubmed/23768515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2013.05.010
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