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Efficient Study Designs for Test of Genetic Association Using Sibship Data and Unrelated Cases and Controls

Linkage mapping of complex diseases is often followed by association studies between phenotypes and marker genotypes through use of case-control or family-based designs. Given fixed genotyping resources, it is important to know which study designs are the most efficient. To address this problem, we...

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Detalhes bibliográficos
Main Authors: Li, Mingyao, Boehnke, Michael, Abecasis, Gonçalo R.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society of Human Genetics 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1474028/
https://ncbi.nlm.nih.gov/pubmed/16642434
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