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Joint Modeling of Linkage and Association: Identifying SNPs Responsible for a Linkage Signal

Once genetic linkage has been identified for a complex disease, the next step is often association analysis, in which single-nucleotide polymorphisms (SNPs) within the linkage region are genotyped and tested for association with the disease. If a SNP shows evidence of association, it is useful to kn...

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Detalhes bibliográficos
Main Authors: Li, Mingyao, Boehnke, Michael, Abecasis, Gonçalo R.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society of Human Genetics 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1196453/
https://ncbi.nlm.nih.gov/pubmed/15877278
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