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Identifying Plausible Genetic Models Based on Association and Linkage Results: Application to Type 2 Diabetes

When planning re-sequencing studies for complex diseases, previous association and linkage studies can constrain the range of plausible genetic models for a given locus. Here, we explore the combinations of causal risk allele frequency RAF(C) and genotype relative risk GRR(C) consistent with no or l...

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Autors principals: Guan, Weihua, Boehnke, Michael, Pluzhnikov, Anna, Cox, Nancy J., Scott, Laura J.
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3578091/
https://ncbi.nlm.nih.gov/pubmed/22865662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.21668
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