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A covering method for detecting genetic associations between rare variants and common phenotypes.

Genome wide association (GWA) studies, which test for association between common genetic markers and a disease phenotype, have shown varying degrees of success. While many factors could potentially confound GWA studies, we focus on the possibility that multiple, rare variants (RVs) may act in concer...

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Detalhes bibliográficos
Main Authors: Gaurav Bhatia, Vikas Bansal, Olivier Harismendy, Nicholas J Schork, Eric J Topol, Kelly Frazer, Vineet Bafna
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2010-10-01
Colecção:PLoS Computational Biology
Acesso em linha:http://europepmc.org/articles/PMC2954823?pdf=render
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