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A Covering Method for Detecting Genetic Associations between Rare Variants and Common Phenotypes

Genome wide association (GWA) studies, which test for association between common genetic markers and a disease phenotype, have shown varying degrees of success. While many factors could potentially confound GWA studies, we focus on the possibility that multiple, rare variants (RVs) may act in concer...

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Detalhes bibliográficos
Main Authors: Bhatia, Gaurav, Bansal, Vikas, Harismendy, Olivier, Schork, Nicholas J., Topol, Eric J., Frazer, Kelly, Bafna, Vineet
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2954823/
https://ncbi.nlm.nih.gov/pubmed/20976246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1000954
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