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Extending Rare-Variant Testing Strategies: Analysis of Noncoding Sequence and Imputed Genotypes
Next Generation Sequencing Technology has revolutionized our ability to study the contribution of rare genetic variation to heritable traits. However, existing single-marker association tests are underpowered for detecting rare risk variants. A more powerful approach involves pooling methods that co...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Elsevier
2010
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2978957/ https://ncbi.nlm.nih.gov/pubmed/21070896 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2010.10.012 |
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