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Imputation of rare variants in next generation association studies
The role of rare variants has become a focus in the search for association with complex traits. Imputation is a powerful and cost-efficient tool to access variants that have not been directly typed, but there are several challenges when imputing rare variants, most notably reference panel selection....
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2013
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3954458/ https://ncbi.nlm.nih.gov/pubmed/23594497 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000345602 |
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