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Testing for rare variant associations in complex diseases
The study of rare variants holds the promise of accounting for some of the missing heritability in complex traits. Next-generation sequencing technologies enable probing of variation across the full spectrum of allele frequencies. Multiple methods for the analysis of rare variants have been proposed...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3129640/ https://ncbi.nlm.nih.gov/pubmed/21542888 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gm238 |
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