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Testing for rare variant associations in complex diseases

The study of rare variants holds the promise of accounting for some of the missing heritability in complex traits. Next-generation sequencing technologies enable probing of variation across the full spectrum of allele frequencies. Multiple methods for the analysis of rare variants have been proposed...

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Bibliografiske detaljer
Main Authors: Asimit, Jennifer, Zeggini, Eleftheria
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3129640/
https://ncbi.nlm.nih.gov/pubmed/21542888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gm238
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