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Next-generation association studies for complex traits
A new study successfully applies complementary whole-genome sequencing and imputation approaches to establish robust disease associations in a population isolate. This strategy is poised to help elucidate the genetic architecture of complex traits in the low end of the allele frequency spectrum.
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3435533/ https://ncbi.nlm.nih.gov/pubmed/21445070 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng0411-287 |
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