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Next-generation association studies for complex traits

A new study successfully applies complementary whole-genome sequencing and imputation approaches to establish robust disease associations in a population isolate. This strategy is poised to help elucidate the genetic architecture of complex traits in the low end of the allele frequency spectrum.

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Autor principal: Zeggini, Eleftheria
Format: Artigo
Idioma:Inglês
Publicat: 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3435533/
https://ncbi.nlm.nih.gov/pubmed/21445070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng0411-287
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