Plumbagin suppresses epithelial to mesenchymal transition and stemness via inhibiting Nrf2-mediated signaling pathway in human tongue squamous cell carcinoma cells

Tongue squamous cell carcinoma (TSCC) is the most common malignancy in oral and maxillofacial tumors with highly metastatic characteristics. Plumbagin (5-hydroxy-2-methyl-1, 4-naphthoquinone; PLB), a natural naphthoquinone derived from the roots of Plumbaginaceae plants, exhibits various bioactiviti...

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Detalhes bibliográficos
Publicado no:Drug Des Devel Ther
Main Authors: Pan, Shu-Ting, Qin, Yiru, Zhou, Zhi-Wei, He, Zhi-Xu, Zhang, Xueji, Yang, Tianxin, Yang, Yin-Xue, Wang, Dong, Zhou, Shu-Feng, Qiu, Jia-Xuan
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2015
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4599573/
https://ncbi.nlm.nih.gov/pubmed/26491260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S89621
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