Plumbagin elicits differential proteomic responses mainly involving cell cycle, apoptosis, autophagy, and epithelial-to-mesenchymal transition pathways in human prostate cancer PC-3 and DU145 cells

Plumbagin (PLB) has exhibited a potent anticancer effect in preclinical studies, but the molecular interactome remains elusive. This study aimed to compare the quantitative proteomic responses to PLB treatment in human prostate cancer PC-3 and DU145 cells using the approach of stable-isotope labelin...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Drug Des Devel Ther
Egile Nagusiak: Qiu, Jia-Xuan, Zhou, Zhi-Wei, He, Zhi-Xu, Zhao, Ruan Jin, Zhang, Xueji, Yang, Lun, Zhou, Shu-Feng, Mao, Zong-Fu
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Dove Medical Press 2015
Gaiak:
Original Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4294653/
https://ncbi.nlm.nih.gov/pubmed/25609920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S71677
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