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Plumbagin induces cell cycle arrest and autophagy and suppresses epithelial to mesenchymal transition involving PI3K/Akt/mTOR-mediated pathway in human pancreatic cancer cells

Plumbagin (PLB), an active naphthoquinone compound, has shown potent anticancer effects in preclinical studies; however, the effect and underlying mechanism of PLB for the treatment of pancreatic cancer is unclear. This study aimed to examine the pancreatic cancer cell killing effect of PLB and inve...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Drug Des Devel Ther
मुख्य लेखकों: Wang, Feng, Wang, Qi, Zhou, Zhi-Wei, Yu, Song-Ning, Pan, Shu-Ting, He, Zhi-Xu, Zhang, Xueji, Wang, Dong, Yang, Yin-Xue, Yang, Tianxing, Sun, Tao, Li, Min, Qiu, Jia-Xuan, Zhou, Shu-Feng
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Dove Medical Press 2015
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4304578/
https://ncbi.nlm.nih.gov/pubmed/25632222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S73689
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