Plumbagin induces cell cycle arrest and autophagy and suppresses epithelial to mesenchymal transition involving PI3K/Akt/mTOR-mediated pathway in human pancreatic cancer cells

Plumbagin (PLB), an active naphthoquinone compound, has shown potent anticancer effects in preclinical studies; however, the effect and underlying mechanism of PLB for the treatment of pancreatic cancer is unclear. This study aimed to examine the pancreatic cancer cell killing effect of PLB and inve...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Drug Des Devel Ther
Egile Nagusiak: Wang, Feng, Wang, Qi, Zhou, Zhi-Wei, Yu, Song-Ning, Pan, Shu-Ting, He, Zhi-Xu, Zhang, Xueji, Wang, Dong, Yang, Yin-Xue, Yang, Tianxing, Sun, Tao, Li, Min, Qiu, Jia-Xuan, Zhou, Shu-Feng
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Dove Medical Press 2015
Gaiak:
Original Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4304578/
https://ncbi.nlm.nih.gov/pubmed/25632222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S73689
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