Llwytho...

Functional Roles of Clusters of Hydrophobic and Polar Residues in the Epithelial Na(+) Channel Knuckle Domain

The extracellular regions of epithelial Na(+) channel subunits are highly ordered structures composed of domains formed by α helices and β strands. Deletion of the peripheral knuckle domain of the α subunit in the αβγ trimer results in channel activation, reflecting an increase in channel open proba...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Biol Chem
Prif Awduron: Chen, Jingxin, Ray, Evan C., Yates, Megan E., Buck, Teresa M., Brodsky, Jeffrey L., Kinlough, Carol L., Winarski, Katie L., Hughey, Rebecca P., Kleyman, Thomas R., Sheng, Shaohu
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4599017/
https://ncbi.nlm.nih.gov/pubmed/26306034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.665398
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