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External Cu(2+) Inhibits Human Epithelial Na(+) Channels by Binding at a Subunit Interface of Extracellular Domains
Epithelial Na(+) channels (ENaCs) play an essential role in the regulation of body fluid homeostasis. Certain transition metals activate or inhibit the activity of ENaCs. In this study, we examined the effect of extracellular Cu(2+) on human ENaC expressed in Xenopus oocytes and investigated the str...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3149337/ https://ncbi.nlm.nih.gov/pubmed/21659509 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.232058 |
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