טוען...
Probing the Structural Basis of Zn(2+) Regulation of the Epithelial Na(+) Channel
Extracellular Zn(2+) activates the epithelial Na(+) channel (ENaC) by relieving Na(+) self-inhibition. However, a biphasic Zn(2+) dose response was observed, suggesting that Zn(2+) has dual effects on the channel (i.e. activating and inhibitory). To investigate the structural basis for this biphasic...
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| Main Authors: | , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
American Society for Biochemistry and Molecular Biology
2012
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3471688/ https://ncbi.nlm.nih.gov/pubmed/22930753 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.394734 |
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